Erectile Dysfunction Treatment in Canada
Clinical efficacy of sildenafil has been evaluated in numerous clinical studies around the world. Carson and other researchers have pooled data from 11 double-blind, placebo-controlled trials involving a total of nearly 3,000 men with ED. After 12 weeks of drug administration improved erection has been noted in 76% of men treated with sildenafil and in 22% treated with placebo, while the percentage of successful sexual intercourse attempts was 66% and 26% in the first and second group, respectively. The effectiveness of different doses of sildenafil was 65% for 25mg, 74% for 50mg and 82% for 100mg.
It is known that hypertension is a risk factor for ED. Although sildenafil has some hypotensive action, it is safe in patients with hypertension, receiving and not receiving antihypertensive drugs. The effectiveness of Viagra Canada in patients with erectile dysfunction suffering from hypertension is quite high. Among patients with hypertension of various origins and receiving placebo and sildenafil erection accompanied by an improvement in 18% and 70%, respectively. Among men who received two or more antihypertensive drugs, these figures were 17.6% and 71%.
Another well-known risk factor for ED is smoking. The usefulness of Viagra among smokers is not inferior to non-smokers (80% and 74% respectively). Various neurological diseases, like depression and anxiety can also be a cause of ED. According to the research, result of Viagra therapy in patients with Parkinson's disease, multiple sclerosis and spinal cord injuries has shown 80% effectiveness.
Specific groups of men with ED, for whom it is difficult to treat - are patients with diabetes and those who had undergone radical prostatectomy (RP). The effectiveness of ED treatment after RP is determined by several factors. According to the study, Viagra treatment was effective in 71.7% of patients after bilateral nerve-sparing RP, 50% after unilateral nerve-sparing RP, and only 15% of patients with ED after non nerve-sparing surgery.
In addition, the feature of erectile dysfunction in these patients is the possibility of a progressive improvement of erection for up to 4 years after surgery. This is confirmed by Hong data, who examined 316 patients with ED after RP, 95% of bilateral nerve-sparing nature. The effectiveness of Viagra was 26% during the first 6 months, 36% in the period from 6 to 12 months, 50% from 12 to 18 months and 60% from 18 to 24 months after surgery.
In patients with diabetes, the effectiveness of Viagra depends on the severity of diabetes and the presence of its complications. Thus, the study of Carson and colleagues has shown, that among diabetic patients without complications has been noted improved erections in 8% of patients receiving placebo and 69% treated with Viagra.